目次

Table of Contents
I. Introduction
II. Major Product Development Opportunities
A. Instrumentation
B. Reagent Kits and Test Systems/panels
C. Computers, Software and Automation
D. Auxiliary Products
III. Design Criteria for Decentralized Testing Products
IV. Alternative Market Penetration Strategies
A. Internal Development
B. Collaborative Arrangements
C. University Contracts
D. Distribution Strategies for Decentralized Testing Markets
V. Potential Market Entry Barriers and Risks
A. Market Maturity
B. Cost Containment
C. Competition
D. Technological Edge and Limitations
E. Patent Protection
F. Regulatory Constraints
G. Decentralized Testing Market Challenges
VI. Worldwide Market and Technology Review
A. DNA Sequencing
1. Introduction
2. Sequencing Methods
3. Autoradiography
4. The Human Genome Project
5. Sequencing Automation
6. Image Scanners
7. Fluorescent Detection
8. Gene Profiling
9. Gene Expression
10. Polymorphism Screening
11. Protein Interaction Networks
　B. DNA and RNA Probe Technologies
　1. Basic Principles
　2. Probe Preparation
　3. The DNA Probe Test
　4. Test Formats
　5. Labeling Techniques
　6. Amplification Methods
C. Detection Technologies
1. Radioactive Methods
　2. Non-Isotopic Methods
　D. Instrumentation
　Review of latest analyzers from Abbott, Beckman Coulter/Danaher, Becton Dickinson,
　bioMerieux, Bio-Rad, Cepheid, Hologic, Qiagen, Roche, Siemens Healthineers, and other suppliers.
　E. Biochips: Genosensors, Microarrays, Labs-on-the-Chip
　- Liquid Transportation and Mixing
　- Separation
　- Reaction
　- Detection
F. Pharmacogenomics
G. Major Applications
1. Cancer Testing
　a. Overview
　b. Major Cancer Types
　 - Prostate
　 - Lung
　 - Colon and Rectum
　 - Breast
　 - Skin
　 - Uterine
　 - Leukemia
　 - Oral
　c. Oncogenes
　 - Abl/abl-bcr
　 - AIB1
　 - BCL-2
　 - BRCA1
　 - CD44
　 - C-fos
　 - C-myb
　 - C-myc
　- CYP17
　- Erb-B
　- HPC1
　- N-myc
　- P40
　- P51
　- P53
　- PIK3CA
　- PTI-1
　- Ras
　- Reg
　- Sis
　- Src
2. Genetic Diseases
　a. Overview
b. Nucleic Acid Amplification
c. Chromosome Imaging
d. Genomics Technologies
e. Proteomics Technologies
f. Current Pharmacogenomic Tests
g. Future Pharmacogenomic Testing
h. Major Diseases
　- Achondroplasia
　- Autosomal Dominant Polycystic Kidney Disease
　- Cancer
　- Cosmetogenomics
　- Cystic Fibrosis
　- Down's Syndrome
　- Duchenne and Becker Muscular Dystrophy
　- Factor V (Leiden)
　- Factor IX Deficiency
　- Fragile X Syndrome
　- Heart Disease
　- Hemochomatosis
　- Hemophilia
　- Huntington's Disease
　- Maternal-Fetal Incompatibility
　- Multiple Endocrine Neoplasia
　- Phenylketonuria (PKU)
　- Polycystic Kidney Disease (PKD)
　- Prenatal Screening
　- Retinitis Pigmentosa
　- Retinoblastoma
　- Sickle Cell Anemia
　- Spinal Muscular Atrophy
　- Vitamin B12 Metabolism
i. Social Issues and Concerns
3. Forensic Testing
　a. Overview
b. Multilocus and Single Locus Probes
c. DNA Profile Data Banks
d. Judicial Implementation
e. Major Crime Categories
f. Factors Contributing to the DNA Probe Market Expansion
　- Technology Availability
　- Use of Hair as Evidence
g. Wildlife Forensics
　4. Paternity Testing/HLA Typing
　5. Other Applications
　a. Disease Susceptibility Testing
　b. Cardiovascular Diseases
　c. Diabetes
　d. Alzheimer's Disease
　e. Periodontal Disease
　f. Plasma Purification
　g. Organ Transplantation
　h. Water Contamination
　i. Other
H. Competing/Complementing
Technologies
1. Monoclonal Antibodies/Immunoassays
2. RNA Probes
3. Two-Dimensional Electrophoresis
4. Flow Cytometry
VII. Country Market Analyses: Molecular Diagnostic Analyzers and Reagent Market Shares and Forecasts
for 100 Tests--Volume and Sales Forecasts
France, Germany, Italy, Spain, UK
VIII. Competitive Assessments
The report provides strategic assessments of over 40 leading molecular diagnostics market players and
start-up companies with innovative technologies and products, including:
Abbott
Agilent Technologies
Applied Gene Technologies
Arca Biopharma
Beckman Coulter/Danaher/Cepheid
Becton Dickinson
Biokit
bioMerieux
Bio-Rad
Decode Genetics
Diasorin
Eiken Chemical
Elitech Group
Enzo Biochem
Exact Sciences
Fujirebio
Grifols
Hologic
Illumina
LabCorp
Leica Biosystems/Kreatech
Li-Cor Biosciences
Myriad Genetics
Proteome Sciences
Qiagen
Quest Diagnostics
QuidelOrtho
Roche
Shimadzu
Siemens Healthineers
Takara Bio
Tecan Group
Thermo Fisher