二重特異性抗体は、過去10年間で勢いを増しているエキサイティングな新しい治療アプローチです。これらの細心の注意を払って設計された分子は、免疫系を利用して悪性細胞やその他の疾患の細胞や組織を正確に標的とする独自の作用機序を提供し、副作用のリスクを最小限に抑える標的アプローチを実現します。過去3年間で、二重特異性抗体の市場は研究開発と商業活動が急速に急増しており、今後数年間で市場が急速に成長することが予想されます。
	二重特異性抗体は、2つの異なる抗原に同時に結合することを目的とした改変タンパク質であり、通常、異なる細胞タイプに見られます。その二重の標的能力は、疾患に対して免疫系を利用する複数の方法を提供します。がんの場合、一般的なアプローチには、悪性細胞を攻撃するためにT細胞またはナチュラルキラー細胞をリダイレクトすることが含まれます。また、免疫細胞と腫瘍細胞を架橋させて、免疫応答を高めることもできます。さらに、2つの異なるシグナル伝達経路を遮断したり、免疫細胞を腫瘍微小環境に動員したりすることができます。
								
						目次
						
	Table of Content
	1. Introduction to Bispecific Antibody
	
	1.1 Overview
	1.2 Clinical Advancement of Bispecific Antibodies
	2. Bispecific Antibodies Combination Strategies
	
	2.1 Chemotherapies
	2.2 Targeted Therapies
	2.3 Immunotherapies
	2.4 Radiotherapy
	3. Commercially Approved Bispecific Antibodies Insight
	
	3.1 Company, Indication, Location and MOA
	3.2 Bispecific Antibodies Granted FDA and EMA Designations
	4. Bispecific Antibodies Proprietary Platforms
	5. Global and Regional Bispecific Antibody Market Outlook
	
	5.1 Yearly and Quarterly Sales Insight (2019 to 2023)
	5.2 Approved Bispecific Antibodies Reimbursement Policy
	5.3 Global Bispecific Antibody Market Forecast 2029
	6. Global Bispecific Antibody Market Trends By Region
	
	6.1 US
	6.2 Europe
	6.3 China
	6.4 UK
	6.5 Japan
	6.6 South Korea
	6.7 Australia
	6.8 Canada
	6.9 Latin America
	7. Global Bispecific Antibodies Research and Market Trends by Indications
	
	7.1 Lymphoma
	7.2 Multiple Myeloma
	7.3 Leukemia
	7.4 Lung Cancer
	7.5 Melanoma
	7.6 Blood Disorders
	7.7 Gastrointestinal Cancers
	7.8 Other Cancers
	7.9 Autoimmune and Inflammatory Diseases
	7.10 Microbial Diseases
	7.11 Ocular Diseases
	8. Global Bispecific Antibodies Clinical Trials Overview
	
	8.1 By Phase
	8.2 By Country/Region
	8.3 By Company
	8.4 By Indication
	8.5 By Priority Status
	8.6 Patient Segment
	9. Blincyto - Clinical, Patent, Pricing and Sales Insight
	
	9.1 Overview and Patent Insight
	9.2 Pricing and Dosage Analysis
	9.3 Sales Analysis
	10. Hemlibra - Clinical, Patent, Pricing and Sales Insight
	
	10.1 Overview
	10.2 Pricing and Dosage Insight
	10.3 Sales Analysis
	11. Rybrevant - Clinical, Patent and Pricing Insight
	
	11.1 Overview
	11.2 Pricing and Dosage Insight
	12. Kimmtrak - Clinical, Patent, Pricing and Sales Insight
	
	12.1 Overview
	12.2 Pricing and Dosage Insight
	12.3 Sales Analysis
	13. Vabysmo - Clinical, Patent, Pricing and Sales Insight
	
	13.1 Overview
	13.2 Pricing and Dosage Insight
	13.3 Sales Analysis
	14. Lunsumio - Clinical, Patent, Pricing and Sales Insight
	
	14.1 Overview and Patent Insight
	14.2 Pricing and Dosage Insight
	14.3 Sales Analysis
	15. Cadonilimab - Clinical and Sales Insight
	16. Tecvayli - Clinical, Patent and Pricing Insight
	
	16.1 Overview and Patent Insight
	16.2 Pricing and Dosage Insight
	17. Columvi - Clinical, Patent, Pricing and Sales Insight
	
	17.1 Overview and Patent Insight
	17.2 Pricing and Dosage Insight
	17.3 Sales Analysis
	18. Epkinly - Clinical, Patent, Pricing and Sales Insight
	
	18.1 Overview
	18.2 Pricing and Dosage Insight
	18.3 Sales Analysis
	19. Talvey - Clinical, Patent and Pricing Insight
	
	19.1 Overview and Patent Insight
	19.2 Pricing and Dosage Insight
	20. Elrexfio - Clinical, Patent and Pricing Insight
	
	20.1 Overview
	20.2 Pricing and Dosage Insight
	21. Global Bispecific Antibodies Clinical Trials By Company, Indication and Phase
	
	21.1 Research
	21.2 Preclinical
	21.3 Phase-I
	21.4 Phase-I/II
	21.5 Phase-II
	21.6 Phase-II/III
	21.7 Phase-III
	21.8 Preregistration
	21.9 Registered
	22. Marketed Bispecific Antibodies Clinical Insight By Company, Country and Indication
	23. Competitive Landscape
	
	23.1 ABL Bio
	23.2 Abzyme Therapeutics
	23.3 Affimed Therapeutics
	23.4 Akeso Biopharma
	23.5 Alligator Bioscience
	23.6 Amgen
	23.7 Antibody Therapeutics
	23.8 APITBIO
	23.9 Aptevo Therapeutics
	23.10 Astellas Pharma
	23.11 AstraZeneca
	23.12 BioAtla
	23.13 Biosion
	23.14 Biotheus
	23.15 BJ Bioscience
	23.16 EpimAb Biotherapeutics
	23.17 FutureGen Biopharmaceutical
	23.18 Genentech
	23.19 Genmab
	23.20 Gensun Biopharma
	23.21 Harbour BioMed
	23.22 IGM Biosciences
	23.23 I-MAB Biopharma
	23.24 ImmuneOnco Biopharma
	23.25 ImmunoPrecise Antibodies
	23.26 Innovent Biologics
	23.27 Invenra
	23.28 Janssen Research and Development
	23.29 Kenjockety Biotechnology
	23.30 LaNova Medicines Limited
	23.31 Light Chain Bioscience
	23.32 Linton Pharm
	23.33 Lyvgen Biopharma
	23.34 MacroGenics
	23.35 Merus
	23.36 NovaRock Biotherapeutics
	23.37 Pfizer
	23.38 Phanes Therapeutics
	23.39 Prestige BioPharma
	23.40 Regeneron Pharmaceuticals
	23.41 Revitope
	23.42 Roche
	23.43 Virtuoso Therapeutics
	23.44 Xencor
	23.45 Y-Biologics
	23.46 Zhejiang Shimai Pharmaceutical
	23.47 Zymeworks
	List of Figures
	Figure 1-1: Bispecific Antibodies - Advantages
	Figure 2-1: Antibody-Chemotherapy Combination - Advantages
	Figure 2-2: Antibody-Chemotherapy Combination - Impending Challenges
	Figure 3-1: Blincyto - Mechanism of Action
	Figure 3-2: Hemlibra - Mechanism of Action
	Figure 3-3: Rybrevant - Mechanism of Action
	Figure 3-4: Regulatory Designations - Benefits
	Figure 4-1: Multiclonics - Distinctive Characteristics
	Figure 4-2: Biclonics - Format
	Figure 4-3: ADAPTIR Bispecific Structure
	Figure 4-4: ADAPTIR-FLEX
	Figure 4-5: BEAT Platform - Multispecific Antibodies
	Figure 4-6: FIT-Ig - Proprietary Bispecific Platform
	Figure 4-7: BiClone format
	Figure 4-8: BioAtla CABs - Features
	Figure 4-9: BioAtla CABs - Benefits
	Figure 4-10: IMBiologic Bispecific Antibodies - Strategy
	Figure 4-11: IMBiologic Bispecific Antibodies - Mechanism of Action
	Figure 4-12: Novel HBICE
	Figure 4-13: HBICE - Mechanism of Action
	Figure 4-14: HBICE - Mechanism of Action
	Figure 4-15: Phanes Therapeutics - PACbody Platform
	Figure 4-16: Phanes Therapeutics - SPECpair Platform
	Figure 4-17: Phanes Therapeutics - ATACCbody
	Figure 4-18: Numab Therapeutics - Technology
	Figure 4-19: Grabody I Platform - Mechanism of Action
	Figure 4-20: Grabody I Platform - Mechanism of Action
	Figure 4-21: 3-Step DuoBody Production Process
	Figure 4-22: DuoHexaBody Molecules - Schematic
	Figure 4-23: iTAb - Patented Structure
	Figure 4-24: iTAb - Mechanism of Action
	Figure 4-25: Synimmune - Proprietary Bispecific Antibody Format
	Figure 4-26: BiTE - Structure
	Figure 4-27: BiTE Molecule
	Figure 4-28: Sanyou Super Trillion Common Light Chain Antibody Discovery Platform
	Figure 4-29: ALiCE - Characteristics
	Figure 4-30: ALiCE - Schematic Diagram and Mechanism of Action
	Figure 4-31: Abz2 Bispecific Platform
	Figure 4-32: Abz2 Bispecifics - Benefits
	Figure 4-33: Neo-X-Prime Bispecific Mechanism
	Figure 4-34: B-Body Bispecific Antibody - Structre
	Figure 4-35: xLinkBsAb - Structure
	Figure 4-36: PrecisionGATE Bispecific Antibody - Structure
	Figure 5-1: Global - Annual Bispecific Antibody Market (US$ Million), 2019-2023
	Figure 5-2: Global - Quarterly Bispecific Antibody Market (US$ Million), 2023
	Figure 5-3: Global - Annual Bispecific Antibodies Market by Drug (US$ Million), 2023
	Figure 5-4: Global - Bispecific Antibodies Market Shares by Drugs (%), 2023
	Figure 5-5: Global - Annual Bispecific Antibody Market by Region (US$ Billion), 2023
	Figure 5-6: Global - Bispecific Antibody Market Shares by Region (%), 2023
	Figure 5-7: Global - Annual Bispecific Antibodies Sales by Drugs (US$ Million), 2022
	Figure 5-8: Global - Bispecific Antibodies Market Shares by Drugs (%), 2022
	Figure 5-9: Global - Bispecific Antibody Market by Region (US$ Million), 2022
	Figure 5-10: Global - Bispecific Antibody Market Shares by Region (%), 2022
	Figure 5-11: US - Annual Bispecific Antibody Market Value (US$ Million), 2019-2023
	Figure 5-12: ROW - Global Bispecific Antibody Market Value (US$ Million), 2019-2023
	Figure 5-13: US - Quarterly Bispecific Antibodies Market (US$ Million), 2023
	Figure 5-14: ROW - Quarterly Bispecific Antibodies Market (US$ Million), 2023
	Figure 5-15: Blincyto - Total Treatment Cost and Reimbursement Cost
	Figure 5-16: Blincyto - In Pocket and Out of Pocket Cost of Treatment
	Figure 5-17: Hemlibra - Total Treatment Cost and Reimbursement Cost
	Figure 5-18: Hemlibra - In Pocket and Out of Pocket Cost of Treatment
	Figure 5-19: Rybrevant - Maximum Coverage by Medicaid (US$), 2023
	Figure 5-20: Rybrevant - Maximum Coverage by Private Insurance Coverage (US$), 2021
	Figure 5-21: Vabysmo - Total Treatment Cost and Reimbursement Cost
	Figure 5-22: Vabysmo - In Pocket and Out of Pocket Cost of Treatment
	Figure 5-23: Global - Bispecific Antibody Market Opportunity Assessment (US$ Billion), 2024 - 2029
	Figure 6-1: US - Bispecific Antibodies Approval
	Figure 6-2: Blincyto - US v/s ROW Sales (US$ Million), 2023
	Figure 6-3: Blincyto - US v/s ROW Shares (%), 2023
	Figure 6-4: Blincyto - US v/s ROW Sales (US$ Million), 2022
	Figure 6-5: Blincyto - US v/s ROW Shares (%), 2022
	Figure 6-6: Hemlibra - US v/s ROW Sales (US$ Million), 2023
	Figure 6-7: Hemlibra - US v/s ROW Shares (%), 2023
	Figure 6-8: Hemlibra - US v/s ROW Sales (US$ Million), 2022
	Figure 6-9: Hemlibra - US v/s ROW Shares (%), 2022
	Figure 6-10: Global - US v/s ROW in Bispecific Antibodies Market (US$ Million), 2023
	Figure 6-11: Global - US v/s ROW Shares in Bispecific Antibodies Market (%), 2023
	Figure 6-12: Global - US v/s ROW in Bispecific Antibodies Market (US$ Million), 2022
	Figure 6-13: Global - US v/s ROW Shares in Bispecific Antibodies Market (%), 2022
	Figure 6-14: Blincyto - US Patent Filing and Expiration Year
	Figure 6-15: Blincyto - EU Patent Expiration
	Figure 6-16: Vabysmo - Canada Patent Numbers Expiration and Approval Year
	Figure 6-17: Hemlibra - Canada Patent Numbers Approval and Expiration Year
	Figure 6-18: Rybrevant - Canada Patent Numbers Approval and Expiration Year
	Figure 6-19: Kimmtrak - Canada Patent Number Approval and Expiration Year
	Figure 7-1: Bispecific Antibodies - Advantages
	Figure 7-2: TG-1801 Phase 1 Study - Initiation and Completion Year
	Figure 7-3: Bispecific Antibodies - Future Opportunities
	Figure 7-4: Mim8 Phase 3 (NCT05053139) Study - Initiation and Completion Year
	Figure 7-5: Mim8 Phase 3 (NCT05878938) Study - Initiation and Completion Year
	Figure 7-6: NXT007 Phase 1/2 (NCT05987449) Study - Initiation and Completion Year
	Figure 7-7: HMB-001 Phase 1/2 (NCT06211634) Study - Initiation and Completion Year
	Figure 7-8: REGN4018 Phase 1/2 (NCT03564340) Study - Initiation and Completion Year
	Figure 7-9: PRV-3279 Phase 2 (NCT05087628) Study - Initiation and Completion Year
	Figure 8-1: Global - Bispecific Antibodies Clinical Pipeline by Phase (Numbers), 2023
	Figure 8-2: Global - Bispecific Antibodies in Clinical Pipeline by Country (Numbers), 2024 till 2029
	Figure 8-3: Global - Bispecific Antibodies in Clinical Pipeline by Company (Numbers), 2024 till 2029
	Figure 8-4: Global - Bispecific Antibodies in Clinical Pipeline by Indication (Numbers), 2023 till 2029
	Figure 8-5: Global - Bispecific Antibodies in Clinical Pipeline by Orphan Status (Numbers), 2023 till 2029
	Figure 8-6: Global - Bispecific Antibodies in Clinical Pipeline by Patient Segment (Numbers), 2023 till 2029
	Figure 9-1: Blincyto - Approval Year by Region
	Figure 9-2: Blincyto - Patent Filing and Expiration Year
	Figure 9-3: Blincyto - Treatment Regimen Cycles (Weeks)
	Figure 9-4: Blincyto - Duration of Treatment Phase and Resting Phase in Induction and Consolidation Cycles for Treatment of MRD-Positive B-cell precursor (Days)
	Figure 9-5: Blincyto - Cost of Single Cycle and Treatment Course for the Treatment of MRD-positive B-cell Precursor ALL
	Figure 9-6: Blincyto - Recommended Number of Induction and Consolidation Treatment Cycle for Relapsed B-Cell Precursor ALL
	Figure 9-7: Blincyto - Duration of Single Induction, Consolidation, Continued Cycle and Full Treatment for Relapsed B-Cell Precursor ALL (Weeks)
	Figure 9-8: Blincyto - Cost of Single Cycle and Treatment Course for Treatment for Relapsed B-Cell Precursor ALL
	Figure 9-9: Global - Blincyto Sales (US$ Million), 2019-2023
	Figure 9-10: Global - Blincyto Sales (US$ Million), Q1 - Q4’2023
	Figure 9-11: Blincyto - US v/s ROW Sales (US$ Million), 2023
	Figure 9-12: Global - Blincyto Sales by Region (%), 2023
	Figure 9-13: US - Blincyto Sales (US$ Million), Q1 - Q4’2023
	Figure 9-14: ROW - Blincyto Sales (US$ Million), Q1 - Q4’2023
	Figure 9-15: US - Blincyto Sales ((US$ Million), 2019-2023
	Figure 9-16: ROW - Blincyto Sales (US$ Million), 2019-2023
	Figure 10-1: Hemlibra - Approval Years by Region
	Figure 10-2: Hemlibra - Cost per Unit and Supply of 150 mg/mL Subcutaneous Injection (US$), February’2024
	Figure 10-3: Hemlibra - Recommended Loading and Maintenance Dose for Treatment of Hemophilia (mg/kg/Week)
	Figure 10-4: Global - Hemlibra Sales (US$ Million), 2019-2023
	Figure 10-5: US - Hemlibra Sales (US$ Million), 2019-2023
	Figure 10-6: Europe - Hemlibra Sales (US$ Million), 2019-2023
	Figure 10-7: Japan - Hemlibra Sales (US$ Million), 2019-2023
	Figure 10-8: ROW - Hemlibra Sales (US$ Million), 2019-2023
	Figure 10-9: Global - US v/s ROW Sales (US$ Million), 2023
	Figure 10-10: Global - Hemlibra Annual Sales by Region (US$ Million), 2023
	Figure 10-11: Global - Hemlibra Sales by Region (%), 2023
	Figure 10-12: Global - Hemlibra Sales (US$ Million), Q1 - Q4’2023
	Figure 10-13: US - Hemlibra Sales (US$ Million), Q1 - Q4’2023
	Figure 10-14: Europe - Hemlibra Sales (US$ Million), Q1 - Q4’2023
	Figure 10-15: Japan - Hemlibra Sales (US$ Million), Q1 - Q4’2023
	Figure 10-16: ROW - Hemlibra Sales (US$/ US$ Million), Q1 - Q4’2023
	Figure 11-1: Rybrevant - Price per Unit and Supply of Intravenous Solution (US$), February’2024
	Figure 11-2: Rybrevant - Recommended Dose Per Cycle by Body Weight (mg)
	Figure 11-3: Rybrevant - Dose Reduction in Patients with Weight less than 80 kg (mg)
	Figure 11-4: Rybrevant - Dose Reduction in Patients with Weight more than 80 Kg (mg)
	Figure 12-1: Kimmtrak - Approval Year by Region
	Figure 12-2: Kimmtrak - Cost Per Unit and Per Vial (US$), February’2024
	Figure 12-3: Global - Annual Kimmtrak Sales (US$ Million), 2021-2023
	Figure 12-4: Global - Quarterly Kimmtrak Sales (US$ Million), 2023
	Figure 12-5: Kimmtrak - Sales by Region (US$ Million), 2023
	Figure 12-6: Kimmtrak - US v/s ROW Market Shares (US$ Million), 2023
	Figure 12-7: Kimmtrak - US v/s ROW Market Shares (%), 2023
	Figure 12-8: US - Quarterly Kimmtrak Sales (US$ Million), 2023
	Figure 12-9: EU - Quarterly Kimmtrak Sales (US$ Million), 2023
	Figure 12-10 ROW - Quarterly Kimmtrak Sales (US$ Million), 2023
	Figure 13-1: Vabysmo - Approval Year by Region
	Figure 13-2: Vabysmo - Price per Unit and Supply of Intravitreal Solution (US$), February’2024
	Figure 13-3: Global - Vabysmo Sales (US$ Million), 2022-2023
	Figure 13-4: Global - Vabysmo US v/s ROW Sales (US$ Million), 2023
	Figure 13-5: Global - Vabysmo Annual Sales by Region (US$ Million), 2023
	Figure 13-6: Global - Vabysmo Annual Sales by Region (%), 2023
	Figure 13-7: US - Vabysmo Sales (US$ Million), 2022-2023
	Figure 13-8: Europe - Vabysmo Sales (US$ Million), 2022-2023
	Figure 13-9: Japan - Vabysmo Sales (US$ Million), 2022-2023
	Figure 13-10: ROW - Vabysmo Sales (US$ Million), 2022-2023
	Figure 13-11: Global - Vabysmo Sales (US$ Million), Q1 - Q4’2023
	Figure 13-12: US - Vabysmo Sales (US$ Million), Q1 - Q4’2023
	Figure 13-13: Europe - Vabysmo Sales (US$ Million), Q1 - Q4’2023
	Figure 13-14: Japan - Vabysmo Sales (US$ Million), Q1 - Q4’2023
	Figure 13-15: ROW - Vabysmo Sales (US$ Million), Q1 - Q4’2023
	Figure 14-1: Lunsumio - Approval Years by Region
	Figure 14-2: US - Price per Unit and Supply of Lunsumio Intravenous Solution (US$), February’2024
	Figure 14-3: EU - Price per Unit and Supply of Lunsumio Intravenous Solution (US$), February’2024
	Figure 14-4: Global - Lunsumio Sales (US$ Million), 2022-2023
	Figure 14-5: US - Lunsumio Sales (US$ Million), 2022-2023
	Figure 14-6: Europe - Lunsumio Sales (US$ Million), 2022-2023
	Figure 14-7: Global - Lunsumio Annual Sales by Region (US$ Million), 2023
	Figure 14-8: Global - Lunsumio Annual Sales by Region (%), 2023
	Figure 14-9:- Global - Lunsumio Sales (US$ Million), Q1 - Q4’2023
	Figure 14-10: US - Lunsumio Sales (US$ Million), Q1 - Q4’2023
	Figure 14-11: Europe - Lunsumio Sales (US$ Million), Q1 - Q4’2023
	Figure 15-1: Annual - Cadonilimab Sales (US$ Million), H2’2022 and H1’2023
	Figure 16-1: Tecvayli - Approval Years by Region
	Figure 16-2: Tecvayli - Patent Acceptance and Expiration Years
	Figure 16-3: US - Cost per Unit and Supply of Tecvayli Subcutaneous Solution (US$), February’2024
	Figure 16-4: EU - Cost per Unit and Supply of Tecvayli Subcutaneous Solution (US$), February’2024
	Figure 17-1: Columvi - Approval Year by Region
	Figure 17-2: US - Price per Unit and Supply of Columvi Intravenous Solution (US$), February’2024
	Figure 17-3: EU - Price per Unit and Supply of Columvi Intravenous Solution (US$), February’2024
	Figure 17-4: Global - Columvi Sales by Region (US$ Million), 2023
	Figure 17-5: Global - Columvi Sales (US$ Million), Q1 - Q4’2023
	Figure 17-6: US - Columvi Sales (US$ Million), Q1 - Q4’2023
	Figure 17-7: Europe - Columvi Sales (US$ Million), Q1 - Q4’2023
	Figure 18-1: Epkinly - Approval Year by Region
	Figure 18-2: US - Cost per Unit and Supply of Epkinly Subcutaneous Solution (US$), February’2024
	Figure 18-3: EU - Cost per Unit and Supply of Epkinly Subcutaneous Solution (US$), February’2024
	Figure 18-4: Global - Epkinly Sales (US$ Million), 2023
	Figure 18-5: Global - Epkinly Sales (US$ Million), Q1 - Q4’2023
	Figure 19-1: Talvey - Approval Year by Region
	Figure 19-2: Talquetamab - FDA and EMA Designation Year
	Figure 19-3: Talvey - Patent Acceptance and Expiration Year
	Figure 19-4: US - Price per Unit and Supply of Talvey Intravenous Solution (US$), February’2024
	Figure 19-5: EU - Price per Unit and Supply of Talvey Intravenous Solution (US$), February’2024
	Figure 20-1: Elrexfio - Approval Years by Region
	Figure 20-2: Elranatamab - FDA and EMA Designation Years
	Figure 20-3: US - Price per Unit and Supply of Elrexfio Subcutaneous Solution (US$), February’2024
	List of Tables
	
	Table 2-1: Bispecific Antibody and Chemotherapy Combinations in Clinical Trials
	Table 2-2: Bispecific Antibody and Targeted Therapy Combinations in Clinical Trials
	Table 2-3: Bispecific Antibody and Immunotherapy Combinations in Clinical Trials
	Table 2-4: Bispecific Antibody and Radiotherapy Combinations in Clinical Trials
	Table 3-1: Approved Bispecific Antibodies
	Table 3-2: US - Bispecific Antibodies with Regulatory Designations
	Table 3-3: EU - Bispecific Antibodies with Regulatory Designations
	Table 3-4: EU - Bispecific Antibodies with Regulatory Designations
	Table 5-1: Epkinly - Billing Unit Application for Doses
	Table 5-2: Talvey - Coverage Summary
	Table 5-3: Talvey - Coding Summary
	Table 5-4: Elrexfio - HCPCS Codes
	Table 5-5: Elrexfio - HCPCS modifiers
	Table 6-1: US - FDA IND Applications Accepted, February’2024
	Table 6-2: EU - Bispecific Antibodies in Late Stage Clinical Trials
	Table 6-3: Bispecific Antibodies in Clinical Trials in Latin America
	Table 7-1: Lymphoma - Bispecific Antibodies in Clinical Trials
	Table 7-2: Multiple Myeloma - Bispecific Antibodies in Clinical Trials
	Table 7-3: Leukemia - Bispecific Antibodies in Clinical Trials
	Table 7-4: Lung Cancer - Bispecific Antibodies in Clinical Trials
	Table 7-5: Melanoma - Bispecific Antibodies in Clinical Trials
	Table 7-6: Digestive System Cancers - Bispecific Antibodies in Clinical Trials
	Table 7-7: Breast Cancer - Bispecific Antibodies in Clinical Trials
	Table 7-8: Gynecological Cancers - Bispecific Antibodies in Clinical Trials
	Table 7-9: Gynecological Cancers - Bispecific Antibodies in Clinical Trials
	Table 9-1: Blincyto - Active Patents
	Table 9-2: Blincyto - Recommended Dosage and Schedule for the Treatment of MRD-positive B-cell Precursor ALL
	Table 9-3: Blincyto - Recommended Dosage and Schedule for Treatment of Relapsed or Refractory B-cell Precursor ALL
	Table 9-4: Blincyto - Recommended Dosage and Schedule for Treatment of Relapsed or Refractory B-cell Precursor ALL
	Table 11-1: Rybrevant - Premedication
	Table 11-2: Rybrevant - Dose Reductions for Adverse Reactions
	Table 11-3: Rybrevant - Recommended Dosage Modifications for Adverse Reactions
	Table 12-1: Kimmtrak - Recommended Dosage for Treatment of Unresectable or Metastatic Uveal Melanoma
	Table 12-2: Kimmtrak - Dose Modifications for Adverse Reactions
	Table 14-1: Lunsumio - Recommended Treatment Cycles
	Table 14-2: Lunsumio - Recommended Premedications
	Table 14-3: Lunsumio - Recommendations for Management of Cytokine Release Syndrome
	Table 16-1: Tecvayli - Dosing Schedule
	Table 16-2: Tecvayli - Recommended Dosage Modifications for Adverse Reactions
	Table 17-1: Columvi - Dosing Schedule (21-Day Treatment Cycles)
	Table 17-2: Columvi - Premedications to be Administered
	Table 17-3: Columvi - Recommendations for Management of Cytokine Release Syndrome
	Table 17-4: Columvi - Recommended Dosage Modification for Neurologic Toxicity (Including ICANS)
	Table 17-5: Columvi - Recommended Dosage Modifications for Other Adverse Reactions
	Table 18-1: Epkinly - Dosage Schedule
	Table 18-2: Epkinly - Recommendations for Management of Cytokine Release Syndrome
	Table 18-3: Epkinly - Recommendations for Management of Immune Effector Cell-Associated Neurotoxicity Syndrome (ICANS)
	Table 18-4: Epkinly - Recommended Dosage Modifications for Other Adverse Reactions
	Table 19-1: Talvey - Weekly Dosing Schedule
	Table 19-2: Talvey - Biweekly Dosing Schedule
	Table 19-3: Talvey - Recommendations for Management of CRS
	Table 19-4: Talvey - Recommendations for Management of Immune Effector Cell-Associated Neurotoxicity Syndrome (ICANS)
	Table 19-5: Talvey - Recommendations for Management of Neurologic Toxicity (excluding ICANS)
	Table 19-6: Talvey - Recommended Dosage Modifications for Other Adverse Reactions
	Table 20-1: Elrexfio - Dosing Schedule
	Table 20-2: Elrexfio - Recommendations for Management of CRS
	Table 20-3: Elrexfio - Recommended Dosage Modifications for Other Adverse Reactions