科学の進歩に伴い、医薬品の研究開発活動は新規かつ革新的な治療法の生成につながり、がん治療の新時代を切り開いています。免疫療法はそのようなアプローチの 1 つで、何年も前から存在していますが、研究者がその治療可能性を解明するために積極的に取り組んでいるのはつい最近のことです。乳がん治療における継続的な技術革新によって、いくつかの新しい免疫療法アプローチの画期的な進歩が可能になりました。
	手術や化学療法などの従来の方法が主な治療選択肢となっていますが、副作用が長期にわたって続くことや、薬剤耐性の発現やがん再発の可能性が高まっていることから、より効果的な治療選択肢の開発が求められています。免疫療法、特に免疫チェックポイント阻害剤の導入は乳がんの治療に変革をもたらし、免疫療法はトリプルネガティブ乳がんなどの悪性度の高い乳がんにも効果的です。
								
						目次
						
	1. Need For Breast Cancer Immunotherapy?
	
	1.1 Overview
	1.2 Breast Cancer Immunotherapy Mechanism Of Action
	1.3 Potential Breast Cancer Biomarkers
	2. Global Breast Cancer Immunotherapy Market Overview
	
	2.1 Breast Cancer Global Market Insight: Yearly and Quarterly Sales (2019 - 2023)
	2.2 Global Breast Cancer Immunotherapy Market Future Outlook (2023 - 2028)
	3. Global Breast Cancer Immunotherapy Trend Analysis
	
	3.1 US
	3.2 UK
	3.3 Canada
	3.4 Europe
	3.4.1 Germany
	3.4.2 France
	3.4.3 Italy
	3.4.4 Spain
	3.4.5 Poland
	3.4.6 Belgium
	3.5 Australia
	3.6 China
	3.7 Japan
	3.8 South Korea
	3.9 India
	4. Global Breast Cancer Immunotherapy Approved Drugs Sales, Price, Dosage and Patent Analysis
	
	4.1 Keytruda (Pembrolizumab)
	4.2 Perjeta (Pertuzumab)
	4.3 Kadcyla (Ado-Trastuzumab Emtansine)
	4.4 Phesgo (pertuzumab trastuzumab hyaluronidase)
	4.5 Trodelvy (Sacituzumab Govitecan)
	4.6 Herceptin (Trastuzumab)
	4.7 Enhertu (Fam-Trastuzumab Deruxtecan)
	4.8 Margenza (Margetuximab)
	4.9 Tecentriq (Atezolizumab)
	4.10 Avastin (Bevacizumab)
	5. Global Breast Cancer Immunotherapies Clinical Trials Insight
	
	5.1 By Biomarker
	5.2 By Company
	5.3 By Country
	5.4 By Patient Segment
	5.5 By Phase
	6. Global Breast Cancer Immunotherapies Clinical Trials By Company, Country and Indication
	
	6.1 Research
	6.2 Preclinical
	6.3 Phase-I
	6.4 Phase-I/II
	6.5 Phase-II
	6.6 Phase-II/III
	6.7 Phase-III
	6.8 Preregistration
	6.9 Registered
	7. Marketed Breast Cancer Immunotherapies Clinical Insight
	8. Therapeutic Approaches To Breast Cancer Immunotherapy
	
	8.1 Monotherapeutic Approaches
	8.2 Combination Therapy Approach
	8.2.1 Combination Of Targeted Therapy and Endocrine Therapy
	8.2.2 Combination With Immunotherapy
	8.2.3 Combination Strategies That Include Triple Agents
	9. New Immunotherapeutic Approaches In Trials For Breast Cancer Treatment
	
	9.1 Emerging Molecular Targets For CAR T Cell Immunotherapy
	9.2 Bispecific Antibodies
	9.3 Vaccine Based Therapy
	9.4 Oncolytic Viruses
	9.5 Immunotherapy with Tumor Infiltrating Lymphocytes (TILs)
	9.6 Cytokine Therapy
	10. Global Breast Cancer Immunotherapy Market Dynamics
	
	10.1 Market Drivers
	10.2 Market Challenges
	11. Competitive Landscape
	
	11.1 Roche
	11.2 Genentech
	11.3 Amgen
	11.4 Antibody Therapeutics
	11.5 Pfizer
	11.6 Merck
	11.7 Novartis
	11.8 Bristol-Myers Squibb
	11.9 EirGenix
	11.10 Prestige BioPharma
	11.11 Novartis Oncology
	11.12 Protheragen
	11.13 Merck
	11.14 LeadArtis
	11.15 Mayo Clinic
	11.16 Biocad
	11.17 Therabest Korea
	11.18 EpiThany
	11.19 AstraZeneca
	11.20 PACT Pharma
	11.21 Xuanzhu Biopharmaceutical
	11.22 Samsung Bioepis
	11.23 Shanghai Novamab Biopharmaceuticals
	11.24 ImmunityBio
	List of Figures & Tables
	
	Figure 1-1: Conventional Treatment Strategies Used for Breast Cancer
	Figure 1-2: Classification of Immunotherapy
	Figure 1-3: Different Immunotherapeutic Approaches
	Figure 1-4: Majorly used current biomarkers for Breast Cancer
	Figure 1-5: Emerging and Novel Biomarkers for Breast Cancer
	Figure 2-1: Global - Breast Cancer immunotherapy Market Sales (US$ Billion), 2019 - 2023
	Figure 2-2: Global - Breast Cancer immunotherapy Market Quarterly Sales (US$ Billion)’ 2022
	Figure 2-3: Global - Breast Cancer immunotherapy Market By Drug (US$ Million), Q1’2023
	Figure 2-4: Global - Breast Cancer immunotherapy Market By Drug (US$ Million), 2022
	Figure 2-5: US - Breast Cancer immunotherapy Market (US$ Billion)’ 2019 - 2023
	Figure 2-6: US - Breast Cancer immunotherapy Market By Drug (US$ Million), Q1’2023
	Figure 2-7: US - Breast Cancer immunotherapy Market By Drug (US$ Million), 2022
	Figure 2-8: Europe - Breast Cancer immunotherapy Market (US$ Million)’ 2019 - 2023
	Figure 2-9: Europe - Breast Cancer immunotherapy Market By Drug (US$ Million), Q1’2023
	Figure 2-10: Europe - Breast Cancer immunotherapy Market By Drug (US$ Million), 2022
	Figure 2-11: Global - Breast Cancer immunotherapy Market Sales (US$ Billion), 2023 - 2028
	Figure 3-1: US - Share of Breast Cancer Cases In Total Cancer Cases, 2022
	Figure 3-2: US - Reimbursement System
	Figure 3-3: UK - Share of Breast Cancer Cases In Total Cancer Cases, 2020
	Figure 3-4: UK - Key Reimbursement Stakeholders
	Figure 3-5: Canada - Share of Breast Cancer Cases In Total Cancer Cases, 2020
	Figure 3-6: Canada - Drug Reimbursement Process
	Figure 3-7: Europe - Share of Breast Cancer Cases In Total Cancer Cases, 2020
	Figure 3-8: Germany - Reimbursement Of Drugs
	Figure 3-9: France - Drug Pricing and Reimbursement Process
	Figure 3-10: Italy - Drug Pricing and Reimbursement Process
	Figure 3-11: Spain - Pricing and Reimbursement Process
	Figure 3-12: Poland - Stages Of Reimbursement Decision Making Process
	Figure 3-13: Australia - Drug Payment Process
	Figure 3-14: China - Share of Breast Cancer Cases In Total Cancer Cases, 2020
	Figure 3-15: China - Negotiation Process for National Reimbursement Drug List (NRLD)
	Figure 3-16: Japan - Share of Breast Cancer Cases In Total Cancer Cases, 2020
	Figure 3-17: Japan - Reimbursement Process For Public Insured Medical Services
	Figure 3-18: South Korea - Share of Breast Cancer Cases In Total Cancer Cases, 2020
	Figure 3-19: South Korea - Flow Of Reimbursement Decision making For New Drug
	Figure 4-1: Global - Keytruda Annual Sales (US$ Million), 2019 - 2023
	Figure 4-2: Global - Keytruda Quarterly Sales (US$ Million), 2022
	Figure 4-3: US - Keytruda Annual Sales (US$ Million), 2019 - 2023
	Figure 4-4: US - Keytruda Quarterly Sales (US$ Million), 2022
	Figure 4-5: US - Keytruda Price per Unit and per Vial for 25mg/mL Intravenous Solution (US$), May’2023
	Figure 4-6: Keytruda - List Price of a Supply for 3 and 6 Weeks (US$), May’2023
	Figure 4-7: Keytruda - Cost of Treatment for Different Administration Schedules, May’2023
	Figure 4-8: UK - Keytruda Price per 100mg/4mL Intravenous Solution, May’2023
	Figure 4-9: Keytruda - Patent Expiration Year
	Figure 4-10: Global - Perjeta Annual Sales (US$ Million), 2019 - 2023
	Figure 4-11: Global - Perjeta Quarterly Sales (US$ Million), 2022
	Figure 4-12: US - Perjeta Annual Sales (US$ Million), 2019 - 2023
	Figure 4-13: US - Perjeta Quarterly Sales (US$ Million), 2022
	Figure 4-14: Europe - Perjeta Annual Sales (US$ Million), 2019 - 2023
	Figure 4-15: Europe - Perjeta Quarterly Sales (US$ Million), 2022
	Figure 4-16: Japan - Perjeta Annual Sales (US$ Million), 2019 - 2023
	Figure 4-17: Japan - Perjeta Quarterly Sales (US$ Million), 2022
	Figure 4-18: US - Perjeta per Unit and Price for 420mg/14mL Intravenous Solution (US$), May’2023
	Figure 4-19: Perjeta - Total Cost Of Treatment Cycle (US$), May’2023
	Figure 4-20: UK - Perjeta Price per Vial of 420mg/14mL, May’2023
	Figure 4-21: Perjeta - Patent Filing Year v/s Expiration Year - US, Canada and Australia
	Figure 4-22: Global - Kadcyla Annual Sales (US$ Million), 2019 - 2023
	Figure 4-23: Global - Kadcyla Quarterly Sales (US$ Million), 2022
	Figure 4-24: US - Kadcyla Annual Sales (US$ Million), 2019 - 2023
	Figure 4-25: US - Kadcyla Quarterly Sales (US$ Million), 2022
	Figure 4-26: Europe - Kadcyla Annual Sales (US$ Million), 2019 - 2023
	Figure 4-27: Europe - Kadcyla Quarterly Sales (US$ Million), 2022
	Figure 4-28: Japan - Kadcyla Annual Sales (US$ Million), 2019 - 2023
	Figure 4-29: Japan - Kadcyla Quarterly Sales (US$ Million), 2022
	Figure 4-30: US - Kadcyla per Unit and Price (US$) For 1 Powder Injection, May’2023
	Figure 4-31: Kadcyla - Cost of Treatment for 100mg and 160mg of Intravenous Powder, May’2023
	Figure 4-32: UK - Kadcyla Price per 180mg and 160mg Vial, May’2023
	Figure 4-33: Kadcyla - Patent Expiration Year - US v/s UK
	Figure 4-34: Global - Phesgo Annual Sales (US$ Million), 2020 - 2023
	Figure 4-35: Global - Phesgo Quarterly Sales (US$ Million), 2022
	Figure 4-36: US - Phesgo Annual Sales (US$ Million), 2019 - 2023
	Figure 4-37: US - Phesgo Quarterly Sales (US$ Million), 2022
	Figure 4-38: Europe - Phesgo Annual Sales (US$ Million), 2019 - 2023
	Figure 4-39: Europe - Phesgo Quarterly Sales (US$ Million), 2022
	Figure 4-40: US - Phesgo Price per Unit for 10mL of 20,000 Units Phesgo Subcutaneous Injection (US$), May’2023
	Figure 4-41: US - Phesgo Price per Unit for 15mL of 30,000 Units Phesgo Subcutaneous Injection (US$), May’2023
	Figure 4-42: Phesgo - Cost of Treatment Cycle (US$), May’2023
	Figure 4-43: UK - Phesgo Price per Unit for 10mL of 600mg/600mg Phesgo Subcutaneous Injection, May’2023
	Figure 4-44: UK - Phesgo Price per Unit for 15mL of 1200mg/600mg Phesgo Subcutaneous Injection, May’2023
	Figure 4-45: Phesgo - Patent Approval and Expiration Year
	Figure 4-46: Global - Trodelvy Annual Sales (US$ Million), 2021 - 2023
	Figure 4-47: Global - Trodelvy Quarterly Sales (US$ Million), 2022
	Figure 4-48: US - Trodelvy Annual Sales (US$ Million), 2021 -2023
	Figure 4-49: US - Trodelvy Quarterly Sales (US$ Millions), 2022
	Figure 4-50: Europe - Trodelvy Annual Sales (US$ Million), 2021 - 2023
	Figure 4-51: Europe - Trodelvy Quarterly Sales (US$ Millions), 2022
	Figure 4-52: Trodelvy - Per Unit and Price for 180mg of Intravenous Powder (US$), May’2023
	Figure 4-53: Trodelvy - Cost of Treatment Cycle (US$), May’2023
	Figure 4-54: UK - Trodelvy Price per 180mg Vial Powder, May’2023
	Figure 4-55: Trodelvy - US v/s UK Patent Expiration Year
	Figure 4-56: Global - Herceptin Annual Sales (US$ Million), 2019 - 2023
	Figure 4-57: Global - Herceptin Quarterly Sales (US$ Million), 2022
	Figure 4-58: US - Herceptin Annual Sales (US$ Millions), 2019 - 2023
	Figure 4-59: US - Herceptin Quarterly Sales (US$ Million), 2022
	Figure 4-60: Europe - Herceptin Annual Sales (US$ Million), 2019 - 2023
	Figure 4-61: Europe - Herceptin Quarterly Sales (US$ Million), 2022
	Figure 4-62: Japan - Herceptin Annual Sales (US$ Million), 2019 - 2023
	Figure 4-63: Japan - Herceptin Quarterly Sales (US$ Million), 2022
	Figure 4-64: US - Herceptin per Unit and Price for 150mg Intravenous Powder For Injection (US$)
	Figure 4-65: Herceptin - Cost of Treatment (Schedule 1) (US$), May’2023
	Figure 4-66: Herceptin - Cost of Treatment (Schedule 1) (US$), May’2023
	Figure 4-67: Herceptin - Cost of Treatment for Metastatic HER2 Overexpressing Breast Cancer (US$), May’2023
	Figure 4-68: UK - Herceptin Price per Vial for 150mg Powder, May’2023
	Figure 4-69: Herceptin - Patent Filing Year v/s Expiration Year - US and Canada
	Figure 4-70: Global - Enhertu Annual Sales (US$ Million), 2020 - 2023
	Figure 4-71: Global - Enhertu Quarterly Sales (US$ Million), 2022
	Figure 4-72: US - Enhertu Annual Sales (US$ Million), 2020 - 2023
	Figure 4-73: US - Enhertu Quarterly Sales (US$ Million), 2022
	Figure 4-74: EU - Enhertu Annual Sales (US$ Million), 2020 - 2023
	Figure 4-75: EU - Enhertu Quarterly Sales (US$ Million), 2022
	Figure 4-76: Japan - Enhertu Annual Sales (US$ Million), 2020 - 2023
	Figure 4-77: Japan - Enhertu Quarterly Sales (US$ Million), 2022
	Figure 4-78: US - Enhertu per Unit and Price for 100 mg Of Intravenous Powder (US$)
	Figure 4-79: UK- Enhertu Price per 100mg Powder, May’2023
	Figure 4-80: Enhertu - Cost of Treatment With 100mg intravenous Powder, May’2023
	Figure 4-81: Margenza - Research and Development Annual Expense (US$ Million), 2020 - 2022
	Figure 4-82: Margenza -Research and Development Quarterly Expense (US$ Million), 2022
	Figure 4-83: US - Margenza Price per Unit for 25mg/mL Intravenous Solution (US$), May’2023
	Figure 4-84: Margenza - Cost of Treatment with Different Volumes of Intravenous Solution, May’2023
	Figure 4-85: Global - Tecentriq Annual Sales (US$ Million), 2019 - 2023
	Figure 4-86: Global - Tecentriq Quarterly Sales (US$ Million), 2022
	Figure 4-87: US - Tecentriq Annual Sales (US$ Million), 2019 - 2023
	Figure 4-88: US - Tecentriq Quarterly Sales (US$ Million), 2022
	Figure 4-89: Europe- Tecentriq Annual Sales (US$ Million), 2019 - 2023
	Figure 4-90: Europe - Tecentriq Quarterly Sales (US$ Million), 2022
	Figure 4-91: Japan - Tecentriq Annual Sales (US$ Million), 2019 - 2023
	Figure 4-92: Japan - Tecentriq Quarterly Sales (US$ Million), 2022
	Figure 4-93: US - Tecentriq Price per Unit for 840mg/14mL and 1200mg/20mL of Intravenous Solution (US$), May’2023
	Figure 4-94: UK - Tecentriq Price per Unit for 840mg/14mL and 1200mg/20mL of Intravenous Solution, May’2023
	Figure 4-95: Tecentriq - Global Patent Approval and Expiration Year
	Figure 4-96: Global - Avastin Annual Sales (US$ Million), 2019 - 2023
	Figure 4-97: Global - Avastin Quarterly Sales (US$ Million), 2022
	Figure 4-98: US - Avastin Annual Sales (US$ Million), 2019 - 2023
	Figure 4-99: US- Avastin Quarterly Sales (US$ Million), 2022
	Figure 4-100: Europe - Avastin Annual Sales (US$ Million), 2019 - 2023
	Figure 4-101: Europe - Avastin Quarterly Sales (US$ Million), 2022
	Figure 4-102: Japan - Avastin Annual Sales (US$ Million), 2019 -2023
	Figure 4-103: Japan - Avastin Quarterly Sales (US$ Million), 2022
	Figure 4-104: US - Avastin Price per Unit for 25mg/mL of Intravenous Solution (US$), May’2023
	Figure 4-105: UK - Avastin Price per Unit for Different Concentrations of Infusion Vial, May’2023
	Figure 5-1: Global - Breast Cancer immunotherapy Drug Clinical Trials By Biomarker, 2023
	Figure 5-2: Global - Breast Cancer immunotherapy Drug Clinical Trials By Company, 2023
	Figure 5-3: Global - Breast Cancer immunotherapy Drug Clinical Trials By Country, 2023
	Figure 5-4: Global - Breast Cancer immunotherapy Drug Clinical Trials By Patient Segment, 2023
	Figure 5-5: Global - Breast Cancer immunotherapy Drug Clinical Trials By Phase, 2023
	Figure 8-1: Available Monotherapeutic Approaches
	Figure 8-2: Available Combinational Therapies
	Figure 9-1: Emerging Immunotherapeutic Approaches Currently In Trial
	Figure 10-1: Current Market Drivers
	Figure 10-2: Current Market Challenges